影响因子：3.466
DOI码：10.1021/acs.jpcb.0c07476
所属单位：China University of Mining and Technology
发表刊物：Journal of Physical Chemistry B (SCI期刊封面文章)
摘要：Phosphorene is a novel two-dimensional nanomaterial with a puckered surface morphology, which has broad potential application prospects in the fields of biology and medicine. Phosphorene nanosheets are easily oxidized and form phosphorene oxide (PO) in an aerobic environment, whose biological effect remains unknown. In this paper, using large-scale molecular dynamics simulations, we show that the PO nanosheets can penetrate into and destructively extract large amounts of phospholipids from the lipid membrane. The PO nanosheets with a higher oxidation concentration have less extraction of phospholipids, while its oxidation mode has no effect on the extraction of phospholipids. Moreover, inserting PO nanosheets into the lipid membrane can enhance the diffusion of phospholipids on the membrane. These findings can shed light on understanding/designing the membrane–nanomaterial interactions.
第一作者：Yezhe Chen
合写作者：Wei Zhang*,Chuanfu Huang,Mei Feng,Yunqiu Yang,Yuanyuan Gou
论文类型：期刊论文
卷号：125
期号：10
页面范围：2636–2643
是否译文：否
发表时间：2021-01-25
收录刊物：SCI
发布期刊链接：https://pubs.acs.org/doi/10.1021/acs.jpcb.0c07476